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Provedor de dados:  BJM
País:  Brazil
Título:  Antimicrobial resistance and virulence gene profiles in P. multocida strains isolated from cats
Autores:  Ferreira,Thais Sebastiana Porfida
Felizardo,Maria Roberta
Gobbi,Debora Dirani Sena de
Moreno,Marina
Moreno,Andrea Micke
Data:  2015-03-01
Ano:  2015
Palavras-chave:  Cat
Pasteurela multocida
Virulence genes
Resistance
Isolation
Resumo:  Cats are often described as carriers of Pasteurella multocida in their oral microbiota. This agent is thought to cause pneumonia, conjunctivitis, rhinitis, gingivostomatitis, abscess and osteonecrosis in cats. Human infection with P. multocida has been described in several cases affecting cat owners or after cat bites. In Brazil, the cat population is approximately 21 million animals and is increasing, but there are no studies of the presence of P. multocida in the feline population or of human cases of infection associated with cats. In this study, one hundred and ninety-one healthy cats from owners and shelters in São Paulo State, Brazil, were evaluated for the presence of P. multocida in their oral cavities. Twenty animals were positive for P. multocida, and forty-one strains were selected and characterized by means of biochemical tests and PCR. The P. multocida strains were tested for capsular type, virulence genes and resistance profile. A total of 75.6% (31/41) of isolates belonged to capsular type A, and 24.4% (10/41) of the isolates were untypeable. None of the strains harboured toxA, tbpA or pfhA genes. The frequencies of the other genes tested were variable, and the data generated were used to build a dendrogram showing the relatedness of strains, which were clustered according to origin. The most common resistance profile observed was against sulfizoxazole and trimethoprim-sulphamethoxazole.
Tipo:  Info:eu-repo/semantics/article
Idioma:  Inglês
Identificador:  http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1517-83822015000100271
Editor:  Sociedade Brasileira de Microbiologia
Relação:  10.1590/S1517-838246120140084
Formato:  text/html
Fonte:  Brazilian Journal of Microbiology v.46 n.1 2015
Direitos:  info:eu-repo/semantics/openAccess
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